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Selections by roundClub teams are located in North America unless otherwise noted.
Round one| # | Player | Nationality | NHL team | College/junior/club team | | 1 | Steven Stamkos | Canada
Round two| # | Player | Nationality | NHL team | College/junior/club team | | 31 | Jacob Markstrom | Sweden
Round threeImage:Fan Fest at [2008 NHL Draft.JPG|thumb|right|Fan Fest]
| # | Player | Nationality | NHL team | College/junior/club team | | 62 | Justin Daniels | United States
Round four;Notes
- The Tampa Bay Lightning's fourth-round pick went to the San Jose Sharks as the result of a trade on June 21, 2008 that sent a fourth-round pick in 2009 and a fifth-round pick in 2010 to Los Angeles in exchange for this pick.
- :Los Angeles previously acquired this pick as the result of a trade on January 20, 2007 that sent Ryan Munce to Tampa Bay in exchange for this pick.
- The Los Angeles Kings' fourth-round pick went to the Washington Capitals as the result of a trade on June 23, 2007 that sent a fourth-round pick in 2007 to Los Angeles in exchange for a sixth-round pick in 2007 and this pick.
- The Columbus Blue Jackets' fourth-round pick went to the Boston Bruins as the result of a trade on June 21, 2008 that sent a fourth and fifth-round pick in 2008 to Columbus in exchange for this pick.
- The Vancouver Canucks' fourth-round pick went to the Buffalo Sabres as the result of a trade on June 21, 2008 that sent a third-round pick in 2008 to Los Angeles in exchange for the Rangers third-round pick in 2008 and this pick.
- :Los Angeles previously acquired this pick as the result of a trade on February 25, 2007 that sent Brent Sopel to Vancouver in exchange for a conditional second-round pick in 2007 and this pick.
- The Chicago Blackhawks' fourth-round pick went to the New York Islanders as the result of a trade on June 21, 2008 that sent Toronto's third-round pick in 2008 to Chicago in exchange for a third-round pick in 2008 and this pick.
- The Nashville Predators' fourth-round pick went to the San Jose Sharks as the result of a trade on June 21, 2008 that sent Toronto's fourth-round pick in 2009 and a seventh-round pick in 2008 to Nashville in exchange for this pick.
- The Boston Bruins' fourth-round pick went to the Columbus Blue Jackets as the result of a trade on June 21, 2008 that sent a fourth-round pick in 2008 to Boston in exchange for a fifth-round pick in 2008 and this pick.
- The New York Rangers' fourth-round pick was re-acquired as the result of a trade on June 21, 2008 that sent a fourth-round pick in 2009 and a seventh-round pick in 2008 to Nashville in exchange for this pick.
- :Nashville previously acquired this pick as the result of a trade on June 20, 2008 that sent Chris Mason to St. Louis in exchange for this pick.
- :St. Louis previously acquired this pick as the result of a trade on February 26, 2008 that sent Christian Backman to New York in exchange for this pick.
- The Washington Capitals' fourth-round pick went to the Calgary Flames as the result of a trade on February 10, 2007 that sent Andrew Ference and Chuck Kobasew to Boston in exchange for Brad Stuart, Wayne Primeau and this pick. The condition – If Calgary does not re-sign Brad Stuart for 2007–08 NHL season they will receive a fourth-round pick in 2008 – was converted on July 3, 2007.
- :Boston previously acquired this pick as the result of a trade on February 1, 2007 that sent Milan Jurcina to Washington in exchange for this pick. The condition – Washington will receive a fourth-round pick in 2008 if Jurcina averages less than 20 minutes per game for the 2007–08 NHL season – the date of conversion is unknown.
- The San Jose Sharks' fourth-round pick went to the Tampa Bay Lightning as the result of a trade on June 21, 2008 that sent a third-round pick in 2008 to San Jose in exchange for a third-round pick in 2009, a fifth-round pick in 2008 and this pick.
- The Philadelphia Flyers' fourth-round pick went to the Columbus Blue Jackets as the result of a trade on June 20, 2008 that sent Colorado's first-round pick in 2008 and a third-round pick in 2008 to Philadelphia for R. J. Umberger and this pick.
- The Dallas Stars' fourth-round pick went to the Ottawa Senators as the result of a trade on June 23, 2007 that sent a fifth and seventh-round pick in 2007 and Phoenix's seventh-round pick in 2007 to Tampa Bay in exchange for this pick.
- :Tampa Bay previously acquired this pick as the result of a trade on July 2, 2006 that sent Darryl Sydor to Dallas in exchange for this pick.
Round fiveImage:Matt Martin - New York Islanders.jpg|thumb|upright|Matt Martin, who holds the record for most hits in a season was selected 148th overall by the New York Islanders.
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