3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase
In enzymology, a is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are ATP and 3-methyl-2-oxobutanoate dehydrogenase, whereas its 3 products are ADP, 3-methyl-2-oxobutanoate dehydrogenase, and phosphate.
This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins. The systematic name of this enzyme class is ATP: phosphotransferase. Other names in common use include kinase, BCK, BCKD kinase, BCODH kinase, branched-chain alpha-ketoacid dehydrogenase kinase, branched-chain 2-oxo acid dehydrogenase kinase, branched-chain keto acid dehydrogenase kinase, branched-chain oxo acid dehydrogenase kinase , and STK2.
In 2012, it was suggested that mutations in the gene which expresses this enzyme could be the cause of a rare form of autism.Literature
