William Shepherd (disambiguation)
William Shepherd is an American astronaut, commander of the Expedition One crew on the International Space Station.
William Shepherd may also refer to:
- William Shepherd (British politician), British Conservative MP, 1945–1966
- William Shepherd (English cricketer), English cricketer
- William Shepherd (Trinidadian cricketer), Trinidadian cricketer
- William Robert Shepherd, U.S. cartographer and historian
- William Shepherd (Massachusetts politician), Massachusetts politician
- Bill Shepherd (American football), American football player
- Billy Shepherd (basketball), American basketball player
- Bill Shepherd (English footballer), English footballer for Liverpool F.C.
- Bill Shepherd (politician), chairman of the Northland Regional Council, New Zealand
- William Shepherd (minister), English dissenting minister and politician
- William James Affleck Shepherd, English illustrator and cartoonist
- Billy Shepherd, pseudonym of Peter Jones, British music journalist
- Billy Shepherd (footballer), English footballer