Charles Middleton
Charles Middleton may refer to:
- Charles Middleton, 2nd Earl of Middleton, Scottish and English politician
- Charles Middleton, 1st Baron Barham, British aristocrat, First Lord of the Admiralty
- Charles Middleton (cricketer), English cricketer
- Charles Middleton (actor), known for his portrayal of Ming the Merciless
- Charlie Middleton (footballer), English footballer
- Charles R. Middleton, president of Roosevelt University from 2002 to 2015
- Charles G. Middleton, chief of the Savannah Fire Department until 2018