Edward Pierce

• Edward Pierce (priest), Welsh Anglican priest and writer
• Edward Pierce (sculptor) English sculptor who created the interior for many of Christopher Wren's churches
• Edward A. Pierce, American businessman and founder of E.A. Pierce & Co.
• Edward C. Pierce, American politician
• Edward L. Pierce, American author
• Edward Pierce (Massachusetts judge)
• Ed Pierce (baseball), former Major League Baseball pitcher
• Ted Pierce, Australian triple Olympic water polo player
• Tedd Pierce, screenwriter of American animated cartoons

In fiction

• Edward Pierce, the protagonist of the novel The [Great Train Robbery (novel)|The Great Train Robbery] by Michael Crichton