List of highways numbered 375Route 375 or Highway 375 may refer to:CanadaManitoba Provincial Road 375New Brunswick Route 375Saskatchewan Highway 375Japan Japan National Route 375United States Interstate 375 Arkansas Highway 375 Florida State Road 375 Georgia State Route 375 Maryland Route 375 Nevada State Route 375 New York State Route 375 Puerto Rico Highway 375 Texas State Highway Loop 375 Virginia State Route 375 Wyoming Highway 375