Jack Matthews

• Jack Matthews (rugby union), Welsh rugby player
• Jack Matthews (author), American author
• Jack Mathews (actor), alternative name of Canadian guitarist and actor Jack Nicholsen from the Leslie Spit Treeo
• Jack Mathews (footballer), Australian rules footballer
• Jack Matthews, character in Our American Cousin
• John H. Matthews, known as Jack, politician
• Jack Matthews (hurdler), 1955 NCAA 220 yards hurdles runner-up for the Iowa Hawkeyes track and field team