James Greene
James Greene may refer to:
- James Greene (speaker), American politician and Speaker of the Rhode Island House of Deputies
- James Durrell Greene, American inventor and Civil War Brevet Brig. General
- James Edward Greene, Liberian politician
- James Greene (American actor), actor on Broadway and in Philadelphia Experiment II
- James Greene (Canadian politician), leader of the Progressive Conservative Party of Newfoundland
- James Greene (MP), English parliamentarian
- James Greene (Northern Irish actor), television actor
- James Greene (swimmer), American Olympic swimmer
- James K. Greene, member of the Alabama House of Representatives
- James Tyler Greene, American baseball player
- Jim Greene, Irish hurling player
- Jimmy Greene, American musician