James Powers
James Powers may refer to:
- J. F. Powers, American novelist and short-story writer
- James Legrand Powers, founder of Powers Accounting Machine Company
- James Powers (New York politician), New York politician
- James E. Powers, New York politician
- James F. Powers, New Hampshire politician
- James T. Powers, American stage actor, vocalist, and lyricist
- James Patrick Powers, American Roman Catholic bishop
- James Powers (runner), American miler, runner-up at the 1916 USA Outdoor Track and Field Championships