James Wharton
James Wharton may refer to:
- James Wharton, Baron Wharton of Yarm, British politician
- James Wharton (author), author and LGBT activist
- James Wharton (boxer), English boxer
- James Wharton (cricketer), English cricketer
- James Wharton (racing driver), Australian racing driver
- James Edward Wharton, United States Army officer
- J. Ernest Wharton, U.S. Representative from New York