Joseph Spence
Joe or Joseph Spence may refer to:
- Joseph Spence (musician), Bahamian singer and guitarist
- Joseph Spence (author), literary scholar and anecdotist
- Joseph Spence (headmaster), Headmaster of Dulwich College, England, 2009-
- Joe Spence (footballer, born 1898), English international football player for Manchester United
- Joe Spence (footballer, born 1925), English football player for York City