List of highways numbered 450

• Florida State Road 450
• Indiana State Road 450
• Iowa Highway 450
• Manitoba Provincial Road 450
• Maryland Route 450
• Mississippi Highway 450
• New Brunswick Route 450
• New Mexico State Road 450
• Newfoundland and Labrador Route 450
• Ohio State Route 450
• Puerto Rico Highway 450
• Route 450 (Japan)
• U.S. Route 450
• Wyoming Highway 450