Sodium-dependent neutral amino acid transporter B(0)AT2


Sodium-dependent neutral amino acid transporter BAT2 is a protein that in humans is encoded by the SLC6A15 gene.

Function

SLC6A15 shows structural characteristics of an Na+ and Cl−-dependent neurotransmitter transporter, including 12 transmembrane domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites.

Clinical relevance

Variants of this gene linked with depression are associated with reduced SLC6A15 expression in the human hippocampus, as well as decreased volume of this brain region.