William Rutherford
William Rutherford may refer to:
- Bill Rutherford, British professor of biochemistry
- Bill Rutherford (footballer), Scottish footballer
- Bill Rutherford (politician), Oregon politician
- William Gunion Rutherford, Scottish scholar
- William Rutherford (mathematician), English mathematician
- William Rutherford (physiologist), British physiologist
- Sir William Rutherford, 1st Baronet, British politician, MP for West Derby and Edge Hill
- Willie Rutherford, Australian football player